About the Industrial Pharmacy Lab
Instrumentation and Equipment
IPHL is equipped with a wide range of modern research technologies to support analytical, preformulation, and formulation development of a variety of drug delivery systems. Instrumentation and equipment at IPHL include:
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- Single and multi-station tablet presses–B and D tooling
- V Blender
- High shear granulators
- Fluid bed coater and Vector pan coater
- Retsch mill, jet mill, and Quadro Comil for micronization and nano-sizing
- Buchi spray dryer
- Fully programmable VirTis lyophilizer
- 3-D printer
- Mini extruder
- Carver press
- Sonifiers and homogenizers
- Regular and ultra-centrifuges
- Ultra low freezers for sample storage
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- FTIR
- Brookfield viscometers
- Malvern Zetasizer and Mastersizer
- VanKel tap density
- Autograph for tensile, compression, impact, and hardness measurement
- Tablet hardness, friability, and disintegration
- Microscopy and scanning electron microscopy (SEM)
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- Agilent, Waters and Shimadzu HPLC systems with DAD and fluorescence detectors
- LCMS with triple quad MS capability
- Automated ELISA equipment
- SDS-PAGE electrophoresis
- Dissolution studies
- Stability studies
- KF and IR moisture analysis
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- DSC and mDSC
- TGA
- ITC
- Hot stage microscopy
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- Biotek Plate reader
- Circular dichroism spectroscopy
- UV spectrophotometer
Services and Capabilities
Specializing in comprehensive preclinical development, IPHL has the ability to take clients across the entire lifecycle of a drug candidate—from discovery, PK/PD modeling, and analytical support to preformulation and formulation.
All IPHL services are completed in a GLP-compliant environment. IPHL also offers hands-on training and certification courses in several areas of drug development.
Our capabilities include, but are not limited to:
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- UV, fluorescence, and circular dichroism spectroscopy
- HPLC, LCMS
- ELISA, cell-based biological assays
- Stability studies
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- Particle size
- Morphology and polymorphism
- Thermal analysis
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- Excipient compatibility
- Solubility screening
- Hot-melt feasibility
- Particle size reduction
- Lyophilization cycle development
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- Oral solid dosage forms
- Ophthalmic delivery
- Parenteral drug delivery systems
- Lipid based systems, nano-microsphere, and disperse systems
- Protein formulations
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For more information, please contact Dr. Pardeep Gupta.
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- ADME studies in several animal species, metabolic profile using metabolomics software
- Animal studies in a fully staffed AAALAC-accredited vivarium facility on campus
- Bioanalytical support
Training Courses
Through the Industrial Pharmacy Lab, Saint Joseph's offers a variety of education and training courses to advance the knowledge of pharmacy professionals in the areas of preformulation and formulation development.
All of our courses contain didactic and hands-on laboratory components. IPHL courses include:
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- Solid dosage form development
- Controlled release systems
- Spray drying
- Lyophilization
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- Unit operations
- DOE and QbD
- Preformulation
- Formulation development
- Basic animal techniques
- Protein formulation
- Analytical and bioanalytical method development
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- HPLC and LCMS
- Solubility
- Protein characterization
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For more information, please contact Dr. Pardeep Gupta.